About OTP

The One Touch Pipeline (OTP) was developed with the purpose to organize and process NGS data in an automated, organized and scalable way. OTP also provides a user management interface to control secure data access.

All processing workflows available in OTP are triggered automatically to remove the burden of routine tasks from scientists. The processing steps are stored in the database to allow reproducibility.

An automated notification system ensures keeping the user up-to-date about the processing progress. Meta-information and processing results can be explored in the user interface of OTP.

Currently, the following pipelines are offered:

WGS Exome ChIP-seq RNA WGBS 10x_scRNA
Alignment human
mouse
human
mouse
human
mouse
human
mouse
human
mouse
Cell Ranger count human
mouse
SNV human human
Indel human human
SV (Sophia) human human
CNV (ACESeq) human
runYapsa human human

In the context of the German Network for Bioinformatics Infrastructure (de.NBI), OTP is provided to the German bioinformatics community as a service. This distribution of OTP is supported by the BMBF-funded Heidelberg Center for Human Bioinformatics (HD-HuB) within de.NBI.

For further information please refer to our FAQs or contact odcf-service@dkfz-heidelberg.de.

References
[1] Reisinger, E., Journal of Biotechnology (2017), http://dx.doi.org/10.1016/j.jbiotec.2017.08.006