About OTP
The One Touch Pipeline (OTP) was developed with the purpose to organize and process NGS data in an automated, organized and scalable way. OTP also provides a user management interface to control secure data access.
All processing workflows available in OTP are triggered automatically to remove the burden of routine tasks from scientists. The processing steps are stored in the database to allow reproducibility.
An automated notification system ensures keeping the user up-to-date about the processing progress. Meta-information and processing results can be explored in the user interface of OTP.
Currently, the following pipelines are offered:
| WGS | Exome | ChIP-seq | RNA | WGBS | 10x_scRNA | |
|---|---|---|---|---|---|---|
| Alignment | human mouse |
human mouse |
human mouse |
human mouse |
human mouse |
|
| Cell Ranger count | human mouse |
|||||
| SNV | human | human | ||||
| Indel | human | human | ||||
| SV (Sophia) | human | human | ||||
| CNV (ACESeq) | human | |||||
| runYapsa | human | human |
In the context of the German Network for Bioinformatics Infrastructure (de.NBI), OTP is provided to the German bioinformatics community as a service. This distribution of OTP is supported by the BMBF-funded Heidelberg Center for Human Bioinformatics (HD-HuB) within de.NBI.
For further information please refer to our FAQs or contact odcf-service@dkfz-heidelberg.de.
References
[1] Reisinger, E., Journal of Biotechnology (2017), http://dx.doi.org/10.1016/j.jbiotec.2017.08.006